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Posterior cortical atrophy ( PCA ), also called Benson's syndrome, is a rare form of dementia which is considered a visual variant or an atypical variant of Alzheimer's disease (AD). [ 1][ 2][ 3] The disease causes atrophy of the posterior part of the cerebral cortex, resulting in the progressive disruption of complex visual processing. [ 4]
DaT scan. DaT Scan ( DaT scan or Dopamine Transporter Scan) commonly refers to a diagnostic method, based on SPECT imaging, to investigate if there is a loss of dopaminergic neurons in striatum. The term may also refer to a brand name of Ioflupane (123I) tracer used for the study. The scan principle is based on use of the radiopharmaceutical ...
The diagnosis of Alzheimer's disease typically requires a microscopic analysis of plaques and tangles in brain tissue, usually at autopsy. [40] However, Aβ plaques (along with cerebral Aβ-amyloid angiopathy ) can be detected in the brains of living subjects by preparing radiolabeled agents that bind selectively to Aβ deposits in the brain ...
Alzheimer's Disease Neuroimaging Initiative. Alzheimer's Disease Neuroimaging Initiative ( ADNI) is a multisite study that aims to improve clinical trials for the prevention and treatment of Alzheimer's disease (AD). [1] This cooperative study combines expertise and funding from the private and public sector to study subjects with AD, as well ...
Specialty. Radiology, neurology. Amyloid-related imaging abnormalities ( ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease. ARIA is associated with anti-amyloid drugs, particularly human monoclonal antibodies such as aducanumab. [ 1] There are two types of ARIA: ARIA-E and ARIA-H.
Creutzfeldt–Jakob disease ( CJD ), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease. [ 4][ 1] Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. [ 4] Later symptoms include dementia, involuntary movements ...
Corticobasal degeneration. Corticobasal degeneration ( CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [ 1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
Diagnosis may include taking the person's medical history, a physical exam, assessment of neurological function, brain imaging, neuropsychological testing to assess cognitive function, [2] [127] sleep studies, myocardial scintigraphy, [25] or laboratory testing to rule out conditions that may cause symptoms similar to dementia, such as abnormal ...