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Prednisolone is a corticosteroid, a steroid hormone used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. [ 5][ 6] Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. [ 6]
Micrograph of fatty liver, as may be seen due to long-term prednisone use. Trichrome stain.. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. [25]
Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [ 4][ 5][ 6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. Methylprednisolone and its derivatives can be administered ...
Budesonide. Budesonide, sold under the brand name Pulmicort, among others, is a steroid medication. [ 8] It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. [ 8][ 9] The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). [ 8][ 10][ 11] The nasal ...
Trenbolone acetate was discovered in 1963 and was introduced for veterinary use in the early 1970s. [ 5][ 10][ 11] In addition to its veterinary use, trenbolone acetate is used to improve physique and performance, and is purchased from black market suppliers. [ 5] The drug is a controlled substance in many countries and so non-veterinary use is ...
Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor [ 1] that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau ( gluco se + cort ex + ster oid) and ...
Chemical class. Steroids. Legal status. In Wikidata. Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances ( electrolyte balance and fluid balance ). The primary mineralocorticoid is aldosterone .