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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Its use is not recommended in young children or the elderly. [11] [12] There is no clear risk of harm when used during pregnancy; however, use during breastfeeding is not recommended. [13] It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
Gestational diabetes is a condition in which a person without diabetes develops high blood sugar levels during pregnancy. [ 2] Gestational diabetes generally results in few symptoms; [ 2] however, it increases the risk of pre-eclampsia, depression, and of needing a Caesarean section. [ 2] Babies born to individuals with poorly treated ...
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16] [17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
Vas-occlusive contraception is a form of male contraception that blocks sperm transport in the vas deferens, the tubes that carry sperm from the epididymis to the ejaculatory ducts. Vas-occlusive contraception provides a contraceptive effect through physical blockage of the vas deferens, the duct connecting the epididymis to the urethra.
Pre-exposure prophylaxis is a general term for the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent. The term PrEP now typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. [ 1] PrEP is one of a number of HIV prevention strategies for ...
e. Sexual and reproductive health ( SRH) [ 1] is a field of research, health care, and social activism that explores the health of an individual's reproductive system and sexual well-being during all stages of their life. [ 2][ 3][ 4] Sexual and reproductive health is more commonly defined as sexual and reproductive health and rights, [ 5] to ...