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  2. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3][ 5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2] Reintroduced 2002 with restricted indication and ...

  3. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...

  4. Idiopathic hypersomnia - Wikipedia

    en.wikipedia.org/wiki/Idiopathic_hypersomnia

    Idiopathic hypersomnia (IH) is a neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness (EDS). [ 1] Idiopathic hypersomnia was first described by Bedrich Roth in 1976, and it can be divided into two forms: polysymptomatic and monosymptomatic. [ 2][ 3] The condition typically becomes evident in ...

  5. Somnifacient - Wikipedia

    en.wikipedia.org/wiki/Somnifacient

    Somnifacient (from Latin somnus, sleep [1] ), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines . Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2]

  6. Suvorexant - Wikipedia

    en.wikipedia.org/wiki/Suvorexant

    Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]

  7. List of investigational sleep drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.

  8. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon is taken by mouth. [ 3] Side effects of ramelteon include somnolence, dizziness, fatigue, nausea, exacerbated insomnia, and changes in hormone levels. [ 3] Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [ 3] The half-life and duration of ramelteon are much longer than those ...

  9. Drugs You Don't Need For Disorders You Don't Have - The ...

    highline.huffingtonpost.com/articles/en/sleep...

    After Belsomra hit the market, Consumer Reports asked Schwartz to create a label for it. Her version presents the data on the drug in an even-handed way, noting that its ability to aid sleep is “modest” at the highest approved doses. “Short track record means that new, unexpected side effects are possible,” it explains.

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