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Nicotine poisoning. Nicotine poisoning describes the symptoms of the toxic effects of nicotine following ingestion, inhalation, or skin contact. Nicotine poisoning can potentially be deadly, though serious or fatal overdoses are rare. [ 1] Historically, most cases of nicotine poisoning have been the result of use of nicotine as an insecticide ...
Green Tobacco Sickness ( GTS) is a type of nicotine poisoning caused by the transdermal absorption of nicotine from the surface of tobacco plants. [ 1] Tobacco plants that have yet to be cured are referred to as "green tobacco". Nicotine is a water soluble chemical, therefore the risk of GTS is elevated if this chemical from the tobacco plants ...
The initial symptoms of nicotine poisoning may include rapid heart rate, sweating, feeling sick, and throwing up, and delayed symptoms include low blood pressure, seizures, and hypoventilation. [120] Rare serious effects included coma, seizure, trouble breathing, and heart attack. [121]
The onset of these symptoms is very fast, nicotine's half-life being only two hours. [150] The psychological dependence may linger for months or even many years. Unlike some recreational drugs, nicotine does not measurably alter a smoker's motor skills, judgement, or language abilities while under the influence of the drug. Nicotine withdrawal ...
Nicotine exposure during brain development may hamper growth of neurons and brain circuits, effecting brain architecture, chemistry, and neurobehavioral activity. [ 1 ] Nicotine changes the way synapses are formed, which can harm the parts of the brain that control attention and learning. [ 6 ]
Serious risks include nicotine poisoning, which includes symptoms like visual disturbances, hyper-salivation, nausea, and vomiting; and continued addiction to nicotine products. [1] Avoiding smoking and other products with nicotine are recommended since it may lead to nicotine overdose. [34]
Nicotine is a hygroscopic, colorless to yellow-brown, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is miscible with water in its neutral amine base form between 60 °C and 210 °C. It is a dibasic nitrogenous base, having K b1 =1×10 −6, K b2 =1×10 −11. [ 163]
Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [ 6]