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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Fetal alcohol spectrum disorders ( FASDs) are a group of conditions that can occur in a person who is exposed to alcohol during gestation. [ 1] FASD affects 1 in 20 Americans, but is highly mis- and under-diagnosed. [ 9] The several forms of the condition (in order of most severe to least severe) are: fetal alcohol syndrome (FAS), partial fetal ...
Pregnancy over the age of 50 has become possible for more women because of advances in assisted reproductive technology, in particular egg donation. Typically, a woman's fecundity ends with menopause, which, by definition, is 12 consecutive months without any menstrual flow at all. During perimenopause, the menstrual cycle and the periods ...
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16] [17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
Large for gestational age ( LGA) is a term used to describe infants that are born with an abnormally high weight, specifically in the 90th percentile or above, compared to other babies of the same developmental age. [ 1][ 2][ 3] Macrosomia is a similar term that describes excessive birth weight, but refers to an absolute measurement, regardless ...
Studies differ in how they define heavy or light cocaine use during pregnancy, and the time period of exposure during pregnancy on which they focus (e.g. first, second, or third trimester. [19] Drug use by mothers puts children at high risk for exposure to toxic or otherwise dangerous environments, and PCE does not present much risk beyond ...
Pre-exposure prophylaxis is a general term for the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent. The term PrEP now typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. [ 1] PrEP is one of a number of HIV prevention strategies for ...
Sex during pregnancy is a low-risk behaviour except when the physician advises that sexual intercourse be avoided, because it may, in some pregnancies, lead to serious pregnancy complications or health issues such as a high-risk for premature labour or a ruptured uterus. [citation needed] Such a decision may be based upon a history of ...