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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Pyridoxine, metoclopramide [ 4] Frequency. ~1% of pregnant women [ 5] Hyperemesis gravidarum ( HG) is a pregnancy complication that is characterized by severe nausea, vomiting, weight loss, and possibly dehydration. [ 1] Feeling faint may also occur. [ 2] It is considered more severe than morning sickness. [ 2]
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16] [17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
Rumination syndrome, or merycism, is a chronic motility disorder characterized by effortless regurgitation of most meals following consumption, due to the involuntary contraction of the muscles around the abdomen. [ 1] There is no retching, nausea, heartburn, odour, or abdominal pain associated with the regurgitation as there is with typical ...
Additionally, it has been found that neuroendocrinology may account for depressive symptoms and stress management due to irregularities in cortisol regulation, and thyroid hormone regulation. [80] Lastly, there is evidence that major depression following TBI is quite common, but may be better accounted for with a diagnosis of dysexecutive syndrome.
Gastroesophageal reflux disease ( GERD) or gastro-oesophageal reflux disease ( GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. [ 6][ 7][ 10] Symptoms include dental corrosion, dysphagia, heartburn, odynophagia ...
Infectious mononucleosis ( IM, mono ), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck ...
Frequency. ~75% of pregnancies [ 4][ 5] Morning sickness, also called nausea and vomiting of pregnancy ( NVP ), is a symptom of pregnancy that involves nausea or vomiting. [ 1] Despite the name, nausea or vomiting can occur at any time during the day. [ 2] Typically the symptoms occur between the 4th and 16th week of pregnancy. [ 2]