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In one April 2023 study, researchers found that one over-the-counter brand of melatonin gummies had more than four-times as much melatonin as its label said. Several contained both melatonin and ...
In the new analysis, 47% of the kids who went to emergency departments had ingested candy-like melatonin gummies, and about half of all visits were caused by a flavored product.
It has become a popular over-the-counter sleeping aid, with sales increasing 150% between 2016 and 2020, the authors said. In the U.S., melatonin is sold as a supplement, not regulated as a drug.
Melatonin is also available as an over-the-counter dietary supplement in many countries. It is available in both immediate-release and less commonly prolonged-release forms. The compound is available in supplements at doses ranging from 0.3 mg to 10 mg or more. It is also possible to buy raw melatonin powder by the weight. [ 39]
As melatonin sales skyrocketed in the U.S., more kids may have had taken the supplement by mistake, experts said.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [ 1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
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