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Sitagliptin, sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. [7] In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. [8] It is taken by mouth. [7] It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet ...
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
SGLT2 inhibitor. SGLT2 inhibitors (also called gliflozins or flozins) are a class of medications that inhibit sodium-glucose transport proteins in the nephron (the functional units of the kidney), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa.
In 2020, it was the 238th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [ 7 ] [ 8 ] It is available as a generic medication . [ 9 ]
Metformin helps manage blood sugar in people with type 2 diabetes in a few different ways: It helps the body respond better to the insulin it makes naturally, decreases the amount of sugar the ...
Dipeptidyl peptidase-4 inhibitor. Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006.
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