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Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Amitriptyline. Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [ 12] Due to the frequency and prominence of side effects, amitriptyline is ...
Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [ 10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [ 10][ 11] For hives it is a less preferred alternative to antihistamines. [ 10] It has a mild to moderate benefit for sleeping problems. [ 12]
Duloxetine is one of the most commonly used prescription medications in the U.S. Patients with depression are usually prescribed 40 to 60 milligrams per day, with a potential increase of up to 120 ...
Tricyclic antidepressants ( TCAs) are a class of medications that are used primarily as antidepressants. TCAs were discovered in the early 1950s and were marketed later in the decade. [ 1] They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms ...
If you've ever popped a Benadryl or two to sleep through a long flight (or even just a regular night), you can pretty much count yourself among the majority of the population.
Benadryl Allergy. Benadryl Allergy is the name of a Benadryl product found in the United States and Canada. It is an antihistamine drug used to relieve allergies. Its active ingredient is diphenhydramine, a first-generation antihistamine. It is known to be sedative, making drowsiness a common side effect.
Anticholinergic. Anticholinergics ( anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [ 1][ 2] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells.
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