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Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping. [ 1][ 11] They may have difficulty falling asleep, or staying asleep for as long as desired. [ 1][ 9][ 12] Insomnia is typically followed by daytime sleepiness, low energy, irritability, and a depressed mood. [ 1] It may result in an increased risk of ...
Magnesium for sleep. There is some research suggesting that magnesium may be beneficial for sleep, according to the experts. A 2023 systematic review of existing studies on magnesium and sleep ...
In sleep medicine, we use very small doses of melatonin multiple hours before bed to help gradually shift the body’s clock (circadian rhythm) in people with delayed sleep phase disorder, jet lag ...
A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
Management of depression is the treatment of depression that may involve a number of different therapies: medications, behavior therapy, psychotherapy, and medical devices . Depression is a symptom of some physical diseases; a side effect of some drugs and medical treatments; and a symptom of some mood disorders such as major depressive ...
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