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  2. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    0.3–0.4% (USA) [ 8] Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [ 3] It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, muscle aches, constipation, slow heart ...

  3. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid function tests ( TFTs) is a collective term for blood tests used to check the function of the thyroid. [ 1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement ...

  4. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [ 1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...

  5. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The hypothalamic–pituitary–thyroid axis ( HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland .

  6. Hyperthyroidism - Wikipedia

    en.wikipedia.org/wiki/Hyperthyroidism

    Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. [ 3] Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. [ 3] Some, however, use the terms interchangeably. [ 5]

  7. Thyroxine-binding globulin - Wikipedia

    en.wikipedia.org/wiki/Thyroxine-binding_globulin

    Thyroxine-binding globulin ( TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. TBG binds thyroid hormones in circulation. It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.

  8. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine ( T3) and thyroxine ( T4 ). They are tyrosine -based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [ 2] A deficiency of iodine leads to decreased ...

  9. Allan–Herndon–Dudley syndrome - Wikipedia

    en.wikipedia.org/wiki/Allan–Herndon–Dudley...

    Increased T3 levels in the blood may be toxic to some organs and contribute to the signs and symptoms of Allan–Herndon–Dudley syndrome. [citation needed] The signature of low T4 and high T3 was for a long time assumed to be caused by either compensatory hyperdeiodination or impaired uptake of T3 in target tissues.