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The human stratum corneum comprises several levels of flattened corneocytes that are divided into two layers: the stratum disjunctum and stratum compactum. The skin's protective acid mantle and lipid barrier sit on top of the stratum disjunctum. [5] The stratum disjunctum is the uppermost and loosest layer of skin. The stratum compactum is the ...
The stratum basale ( basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the external covering of skin in mammals . The stratum basale is a single layer of columnar or cuboidal basal cells. The cells are attached to each other and to the overlying stratum spinosum cells by ...
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals ' skin, and it is very similar to pig skin. Though nearly all human skin is covered ...
The epidermis is composed of 4 or 5 layers, depending on the region of skin being considered. [10] Those layers from outermost to innermost are: [2] cornified layer (stratum corneum) Confocal image of the stratum corneum Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the ...
Skin. Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin ...
The human epidermis is composed of stratified squamous epithelial cells, which further break down into four to five layers: the stratum corneum, stratum granulosum, stratum spinosum and stratum basale. Where the skin is thicker, such as in the palms and soles, there is an extra layer of skin between the stratum corneum and the stratum ...
Stratum granulosum labeled near center. The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis lying above the stratum spinosum and below the stratum corneum ( stratum lucidum on the soles and palms). [ 1] Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer.
Keratinocyte. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [ 1] Basal cells in the basal layer ( stratum basale) of the skin are sometimes referred to as basal keratinocytes. [ 2] Keratinocytes form a barrier against environmental ...