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Liver function tests. Liver function tests ( LFTs or LFs ), also referred to as a hepatic panel, are groups of blood tests that provide information about the state of a patient's liver. [ 1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin, bilirubin (direct and indirect), and others.
Alanine transaminase ( ALT) is a transaminase enzyme ( EC 2.6.1.2 ). It is also called alanine aminotransferase ( ALT or ALAT) and was formerly called serum glutamate-pyruvate transaminase or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues. [ 1]
AST/ALT ratio. LOINC. 16325-3, 1916-6. The AST/ALT ratio or De Ritis ratio is the ratio between the concentrations of two enzymes, aspartate transaminase (AST) and alanine transaminase, aka alanine aminotransferase (ALT), in the blood of a human or animal. It is used as one of several liver function tests, and measured with a blood test.
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1][ 2] Other terms include transaminasemia, [ 3] and elevated liver enzymes (though they are not the only enzymes in the liver).
The transaminase enzymes are important in the production of various amino acids, and measuring the concentrations of various transaminases in the blood is important in the diagnosing and tracking many diseases. [citation needed] For example, the presence of elevated transaminases can be an indicator of liver and cardiac damage.
Aspartate transaminase ( AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase ( GOT, SGOT ), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme ( EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954. [ 1][ 2][ 3] AST catalyzes the reversible transfer of ...
The comprehensive metabolic panel, or chemical screen ( CMP; CPT code 80053), is a panel of 14 blood tests that serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance, but this type of screening has its limitations.
108682 Ensembl ENSG00000166123 ENSMUSG00000031700 UniProt Q8TD30 Q8BGT5 RefSeq (mRNA) NM_133443 NM_001142466 NM_173866 RefSeq (protein) NP_001135938 NP_597700 NP_776291 Location (UCSC) Chr 16: 46.88 – 46.93 Mb Chr 8: 86.22 – 86.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glutamic--pyruvic transaminase 2 is a protein that in humans is encoded by the GPT2 gene. Function This ...