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The cytotoxicity of e-liquids varies, [76] and contamination with various chemicals have been detected in the liquid. [77] E-cigarette vapor potentially contains harmful chemicals which are not found in tobacco smoke. [78] Studies over a year on the effects of exposure to e-cigarettes have not been conducted, as of 2019. [79]
Vaping-associated pulmonary injury ( VAPI ), [ 4] also known as vaping-associated lung injury ( VALI) [ 1] or e-cigarette, or vaping, product use associated lung injury ( E/VALI ), [ 2][ a] is an umbrella term, [ 15][ 16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [ 3]
In 2015 the psychological and behavioral effects of e-cigarettes were studied using whole-body exposure to e-cigarette aerosol, followed by a series of biochemical and behavioral studies. [17] The results showed that nicotine-containing e-cigarette aerosol induces addiction-related neurochemical, physiological and behavioral changes. [17]
An outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI) started in 2019 [ 3] among users of illegal, unregulated cannabis vaping products, [ 2] almost exclusively in the United States. [ 4] The first cases of this particular outbreak were identified in Illinois and Wisconsin in April 2019; as of 18 February 2020, a ...
An electronic cigarette ( e-cigarette) or vape[ note 1][ 1] is a device that simulates tobacco smoking. It consists of an atomizer, a power source such as a battery, and a container such as a cartridge or tank. Instead of smoke, the user inhales vapor. [ 2] As such, using an e-cigarette is often called " vaping ". [ 3]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
Nicotine is a hygroscopic, colorless to yellow-brown, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is miscible with water in its neutral amine base form between 60 °C and 210 °C. It is a dibasic nitrogenous base, having K b1 =1×10 −6, K b2 =1×10 −11. [ 163]
Vaporizer (inhalation device) A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for inhalation. Plant substances can be used, commonly cannabis, tobacco, or other herbs or blends of essential oil. [ 1] However, they are most commonly filled with a combination propylene glycol, glycerin, and drugs ...