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  2. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:

  3. Fetal alcohol spectrum disorder - Wikipedia

    en.wikipedia.org/wiki/Fetal_alcohol_spectrum...

    The use of alcohol during pregnancy occurs at different rates across the world, potentially due to various cultural differences and legislation. The five countries with the highest prevalence of alcohol use during pregnancy are Ireland (60%), Belarus (47%), Denmark (46%), the UK (41%), and the Russian Federation (37%). [28]

  4. Opioids and pregnancy - Wikipedia

    en.wikipedia.org/wiki/Opioids_and_pregnancy

    Opioid use during pregnancy is associated with an increased risk of complications, including an elevated risk of preterm birth, low birth weight, intrauterine growth restriction, and stillbirth. Opioids are substances that can cross the placenta, exposing the developing fetus to the drugs. This exposure can potentially lead to various adverse ...

  5. Flurazepam - Wikipedia

    en.wikipedia.org/wiki/Flurazepam

    Flurazepam. Flurazepam[ 2] (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It produces a metabolite with a long half-life, which may stay in the bloodstream for days. [ 3]

  6. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Non-essential drugs and medications should be avoided while pregnant. Tobacco, alcohol, marijuana, and illicit drug use while pregnant may be dangerous for the unborn baby and may lead to severe health problems and/or ...

  7. Alcohol abuse - Wikipedia

    en.wikipedia.org/wiki/Alcohol_abuse

    Signs of alcohol abuse are related to alcohol's effects on organ systems. However, while these findings are often present, they are not necessary to make a diagnosis of alcohol abuse. Alcohol use disorder causes acute central nervous system depression which leads to inebriation, euphoria, impulsivity, sedation and poor judgment. Chronic alcohol ...

  8. Binge drinking - Wikipedia

    en.wikipedia.org/wiki/Binge_drinking

    Binge drinking during pregnancy is associated with fetal alcohol syndrome, alcohol-related birth defects as well as alcohol-related neurodevelopmental disorders. The affected children after birth may have an intellectual impairment and problems with learning, memory, attention, problem solving and problems with mental health and social ...

  9. Naltrexone - Wikipedia

    en.wikipedia.org/wiki/Naltrexone

    It is unclear if use is safe during pregnancy. [8] [13] Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain. [8] Naltrexone was first made in 1965 and was approved for medical use in the United States in 1984.

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