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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
One of the most well-known consequences of maternal opioid use during pregnancy is the risk of neonatal abstinence syndrome (NAS). NAS occurs when the newborn experiences withdrawal symptoms after birth due to exposure to opioids in the womb. Maternal opioid use during pregnancy can also have long-term effects on the child's development.
Alcohol withdrawal syndrome ( AWS) is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use. [ 1] Symptoms typically include anxiety, shakiness, sweating, vomiting, fast heart rate, and a mild fever. [ 1] More severe symptoms may include seizures, and delirium tremens (DTs); which can be fatal in ...
The use of alcohol during pregnancy occurs at different rates across the world, potentially due to various cultural differences and legislation. The five countries with the highest prevalence of alcohol use during pregnancy are Ireland (60%), Belarus (47%), Denmark (46%), the UK (41%), and the Russian Federation (37%).
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Non-essential drugs and medications should be avoided while pregnant. Tobacco, alcohol, marijuana, and illicit drug use while pregnant may be dangerous for the unborn baby and may lead to severe health problems and/or ...
Flurazepam. Flurazepam[ 2] (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It produces a metabolite with a long half-life, which may stay in the bloodstream for days. [ 3]
t. e. Benzodiazepine withdrawal syndrome ( BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule .
Post-acute withdrawal syndrome ( PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [ 1][ 2] opiates, benzodiazepines, antidepressants, and other substances. [ 3][ 4][ 5] Infants born to mothers who used substances of dependence during pregnancy may also experience a PAWS. [ 6][ 7] While PAWS has ...
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