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The hypothalamic–pituitary–thyroid axis ( HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland .
Numerous symptoms and signs are associated with hypothyroidism and can be related to the underlying cause, or a direct effect of having not enough thyroid hormones. [14] [15] Hashimoto's thyroiditis may present with the mass effect of a goitre (enlarged thyroid gland). [14] In middle-aged women, the symptoms may be mistaken for those of ...
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. [ 1]
Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine ( T3) and thyroxine ( T4 ). They are tyrosine -based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [ 2] A deficiency of iodine leads to decreased ...
Hypopituitarism is the decreased ( hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [ 1][ 2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [ 3] If there is decreased secretion of most or all pituitary ...
Latent inhibition ( LI) is a technical term in classical conditioning, where a familiar stimulus takes longer to acquire meaning (as a signal or conditioned stimulus) than a new stimulus. [ 1] The term originated with Lubow and Moore in 1973. [ 2] The LI effect is latent in that it is not exhibited in the stimulus pre-exposure phase, but rather ...
Thyroxine-binding globulin ( TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. TBG binds thyroid hormones in circulation. It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.
Psychiatry, clinical psychology. Dissociative disorders ( DDs) are a range of conditions characterized by significant disruptions or fragmentation "in the normal integration of consciousness, memory, identity, emotion, perception, body representation, motor control, and behavior." Dissociative disorders involve involuntary dissociation as an ...