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Tirzepatide, the active ingredient in Eli Lilly’s Mounjaro and Zepbound, leads to more weight loss than semaglutide, the active ingredient in Novo Nordisk’s Ozempic and Wegovy, new research ...
Tirzepatide is an antidiabetic medication used for the treatment of type 2 diabetes [ 9][ 12][ 13][ 14] and for weight loss. [ 10][ 15] Tirzepatide is administered via subcutaneous injections (under the skin). [ 9][ 12] It is sold under the brand names Mounjaro for diabetes treatment, [ 9] and Zepbound for weight loss. [ 10]
A 3-year-study of Zepbound and Mounjaro found the GLP-1 drugs can help prevent diabetes. The weekly injections cut the risk of developing diabetes by 94% among adults with high blood sugar.
In Zepbound and Mounjaro, GIP is paired with GLP-1 receptor agonists, and research shows the duo provides "powerful benefits" for blood sugar control and weight reduction. Off-label
In a 2023 randomized clinical trial, 783 participants took tirzepatide (the generic name for Mounjaro and Zepbound) for 36 weeks. Those who stayed on the drug until week 52 lost an additional 5% ...
Zepbound shares the same active ingredient — tirzepatide — as Lilly’s popular diabetes medication Mounjaro. In a phase 3 clinical trial, Zepbound led to an average weight loss of 22.5% body ...
Zepbound vs. Ozempic. Zepbound is specifically approved for weight management in adults with obesity. Ozempic is a Type 2 diabetes treatment to control blood sugar, though it also leads to weight ...
Wegovy and Zepbound have similar side effects. The most common include nausea, diarrhea, vomiting, stomach pain and constipation, according to the drugs’ manufacturers. Some patients find the ...
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