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The unbound or free fraction of levocetirizine has been reported to be 8%. [1] The true volume of distribution of cetirizine is unknown but is estimated to be 0.3 to 0.45 L/kg. [3] [1] Cetirizine poorly and slowly crosses the blood–brain barrier, which is thought to be due to its chemical properties and its activity as a P-glycoprotein substrate.
Moxifloxacin is an antibiotic, used to treat bacterial infections, [ 4 ] including pneumonia, conjunctivitis, endocarditis, tuberculosis, and sinusitis. [ 4 ][ 5 ] It can be given by mouth, by injection into a vein, and as an eye drop. [ 5 ] Common side effects include diarrhea, dizziness, and headache. [ 4 ]
Alcon offices in Johns Creek, Georgia. Alcon Inc. (German: Alcon AG) is a Swiss-American pharmaceutical and medical device company specializing in eye care products. It has a paper headquarters in Geneva, Switzerland but its operational headquarters are in Fort Worth, Texas, United States, where it employs about 4,500 people. [2]
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Ciprodex, owned by Alcon Laboratories, Inc., is protected by multiple patents and will be restricted from generic manufacturing until 2025. [6] [7] Ciprodex is the number 1 topical antibiotic ear drop prescribed since 2007 by ENTs and pediatricians.
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