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Recovery from propofol-induced anesthesia is generally rapid and associated with less frequent side effects [9] [10] (e.g. drowsiness, nausea, vomiting) compared to other anesthetic agents. Propofol may be used prior to diagnostic procedures requiring anesthesia, in the management of refractory status epilepticus , and for induction and/or ...
Propofol infusion syndrome ( PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol. It can lead to cardiac failure, rhabdomyolysis, metabolic acidosis, and kidney failure, and is often fatal. [1] [2] [3] High blood potassium, high blood triglycerides, and ...
Ciprofol. Ciprofol (also known as cipepofol, or HSK3486) [1] is a novel 2,6-disubstituted phenol derivative that is used for the intravenous induction of general anesthesia. [2] [3] A short-acting and highly selective γ-aminobutyric acid agonist, [4] ciprofol is 4–6 times more potent than other phenol derivatives such as propofol or fospropofol.
Sodium thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia.Its use has been largely replaced with that of propofol, but may retain some popularity as an induction agent for rapid-sequence induction and intubation, such as in obstetrics. [12]
Propofol [6] is a non-barbiturate derivative that is thought to act by stimulating inhibitory GABA receptors and blocking excitatory NMDA receptors. It takes 40 seconds for the effects of propofol to kick in, and effects last six minutes. [3] Propofol has both sedative and amnestic effects, but provides no analgesia.
Total intravenous anesthesia ( TIVA) refers to the intravenous administration of anesthetic agents to induce a temporary loss of sensation or awareness. The first study of TIVA was done in 1872 using chloral hydrate, [1] and the common anesthetic agent propofol was licensed in 1986. TIVA is currently employed in various procedures as an ...
Etomidate. Etomidate [3] ( USAN, INN, BAN; marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation [4] for short procedures such as reduction of dislocated joints, tracheal intubation, cardioversion and electroconvulsive therapy. It was developed at Janssen Pharmaceutica in ...
Propofol, an anesthetic medication, confers its own antiemetic properties. Weibel, Rücker, Eberhart et al's 2020 Cochrane review demonstrated that combination therapy is more effective than single anti-emetic, and that dexamethasone and ondansetron (a commonly used combination) are two of the most effective anti-emetics for PONV.