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2. Relaxin - Wikipedia

   en.wikipedia.org/wiki/Relaxin

   Relaxin is a protein hormone of about 6000 Da, [1] first described in 1926 by Frederick Hisaw. [2] [3]The relaxin family peptide hormones belong to the insulin superfamily and consists of seven peptides of high structural but low sequence similarity; relaxin-1 (RLN1), 2 (RLN2) and 3 (), and the insulin-like (INSL) peptides, INSL3, INSL4, INSL5 and INSL6.

3. Sleep induction - Wikipedia

   en.wikipedia.org/wiki/Sleep_induction

   A hot bath before bed may improve the quality of sleep. The daily sleep/wake cycle is linked to the daily body temperature cycle. For this reason, a hot bath which raises the core body temperature has been found to improve the duration and quality of sleep. A 30-minute soak in a bath of 40 degrees Celsius (104 °F) – which raises the core ...

4. Sleep medicine - Wikipedia

   en.wikipedia.org/wiki/Sleep_medicine

   Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and disorders. [1] From the middle of the 20th century, research has provided increasing knowledge of, and answered many questions about, sleep–wake functioning. [2] The rapidly evolving field [3] has become a recognized medical ...

5. Zolpidem - Wikipedia

   en.wikipedia.org/wiki/Zolpidem

   Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]

6. Nonbenzodiazepine - Wikipedia

   en.wikipedia.org/wiki/Nonbenzodiazepine

   A review of the literature regarding hypnotics including the nonbenzodiazepine Z-drugs concluded that these drugs carry a significant risk to the individual. The risks include dependence, accidents, and other adverse effects. Gradual discontinuation of hypnotics may lead to improved health without worsening of sleep.

7. Effects of long-term benzodiazepine use - Wikipedia

   en.wikipedia.org/wiki/Effects_of_long-term...

   Symptoms. Effects of long-term benzodiazepine use may include disinhibition, impaired concentration and memory, depression, [ 19][ 20] as well as sexual dysfunction. [ 6][ 21] The long-term effects of benzodiazepines may differ from the adverse effects seen after acute administration of benzodiazepines. [ 22]