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Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]
Tirzepatide is an analog of the human GIP hormone with a C 20 fatty diacid portion attached, used to optimise the uptake and metabolism of the compound. [ 31] The fatty-diacid section (eicosanedioic acid) is linked via a glutamic acid and two (2- (2-aminoethoxy)ethoxy)acetic acid units to the side chain of the lysine residue.
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Meta Platforms, Inc. (formerly Federal Trade Commission v. Facebook, Inc.) is an ongoing antitrust court case brought by the Federal Trade Commission (FTC) against Facebook parent company Meta Platforms. The lawsuit alleges that Meta has accumulated monopoly power via anti-competitive mergers, with the suit centering on the acquisitions of ...
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