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Doxylamine is used in the combination drug pyridoxine/doxylamine to treat morning sickness (nausea and vomiting of pregnancy). [ 19 ] [ 20 ] [ 21 ] It is the only medication approved by the United States Food and Drug Administration for the treatment of morning sickness.
Dying people, expectant mothers, hesitation, happy death, holy death, interior souls, people in doubt, pioneers, pregnant women, travellers, and fetuses - Joseph; Demons, fever - Patroclus of Troyes [8] Diabetics - Paulina; Invoked against dropsy, childhood sicknesses, hailstones, the pain of childbirth, and gout - Gotthard of Hildesheim
Pyridoxine, metoclopramide [ 4] Frequency. ~1% of pregnant women [ 5] Hyperemesis gravidarum ( HG) is a pregnancy complication that is characterized by severe nausea, vomiting, weight loss, and possibly dehydration. [ 1] Feeling faint may also occur. [ 2] It is considered more severe than morning sickness. [ 2]
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Motion sickness occurs due to a difference between actual and expected motion. [ 1][ 2][ 4] Symptoms commonly include nausea, vomiting, cold sweat, headache, dizziness, tiredness, loss of appetite, and increased salivation. [ 1][ 5] Complications may rarely include dehydration, electrolyte problems, or a lower esophageal tear.
Its use is not recommended in young children or the elderly. [ 11 ] [ 12 ] There is no clear risk of harm when used during pregnancy ; however, use during breastfeeding is not recommended. [ 13 ] It is a first-generation H 1 -antihistamine and it works by blocking certain effects of histamine , which produces its antihistamine and sedative effects.
Geriatrics, or geriatric medicine, [ 1] is a medical specialty focused on providing care for the unique health needs of the elderly. [ 2] The term geriatrics originates from the Greek γέρων geron meaning "old man", and ιατρός iatros meaning "healer". It aims to promote health by preventing, diagnosing and treating disease in older ...
It is similar although more severe than the common morning sickness. [15] [16] It is estimated to affect 0.3–3.6% of pregnant women and is the greatest contributor to hospitalizations under 20 weeks of gestation. Most often, nausea and vomiting symptoms during pregnancy resolve in the first trimester, however, some continue to experience ...