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Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. [1] Some people are genetically more at risk than others. [6] Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. [1]
4.2 million (2019) [ 9] Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [ 10][ 11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [ 12]
Diabetes mellitus occurs throughout the world, but is more common (especially type 2) in the more developed countries. The greatest increase in prevalence is, however, occurring in low- and middle-income countries [ 8 ] including in Asia and Africa, where most patients will probably be found by 2030. [ 9 ]
Eventually, type 2 diabetes occurs when glucose levels become higher as the resistance increases and compensatory insulin secretion fails. [41] [42] The inability of the β-cells to produce sufficient insulin in a condition of hyperglycemia is what characterizes the transition from insulin resistance to type 2 diabetes.
Type 2 diabetes, a chronic condition that occurs when your blood sugar is regularly too high, is the most common type of diabetes, according to the National Institute of Diabetes and Digestive and ...
In type 2 diabetes, insulin production is present but is insufficient to meet the body's requirements as a result of end-organ insulin resistance. Usually, these amounts of insulin are sufficient to suppress ketogenesis. If DKA occurs in someone with type 2 diabetes, their condition is called "ketosis-prone type 2 diabetes". [22]
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