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Typhoon Vera, also known as the Isewan Typhoon (伊勢湾台風, Ise-wan Taifū), was an exceptionally intense tropical cyclone that struck Japan in September 1959, becoming the strongest and deadliest typhoon on record to make landfall on the country, as well as the only one to do so as a Category 5 equivalent storm.
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Believed to be the first coupon ever, this ticket for a free glass of Coca-Cola was first distributed in 1888 to help promote the drink. By 1913, the company had redeemed 8.5 million tickets. [6] Coca-Cola's 1888-issued "free glass of" is the earliest documented coupon. [6] [7] Coupons were mailed to potential customers and placed in magazines ...
[73] Both Facebook and Twitter provide opportunities for brands and companies to offer online coupons and discounts. [73] In a study of online e-cigarette retailers, 28% of the websites offered a promotion, such as a discount, other free items, or a loyalty program. [ 73 ]
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In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
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