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Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1 -adrenergic receptor and has no intrinsic sympathomimetic activity. [ 37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
Sympatholytic. A sympatholytic ( sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS). [ 1] They are indicated for various functions; for example, they may be used as antihypertensives.
Succinic acid (/ s ə k ˈ s ɪ n ɪ k /) is a dicarboxylic acid with the chemical formula (CH 2) 2 (CO 2 H) 2. [5] In living organisms, succinic acid takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex 2 of the electron transport chain which is involved in making ...
Eplerenone. Eplerenone, sold under the brand name Inspra, is an aldosterone antagonist type of potassium-sparing diuretic that is used to treat chronic heart failure and high blood pressure, particularly for people with resistant hypertension due to elevated aldosterone.
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Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class. [2] It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, [2] [3] [4] as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous ...
Atrial fibrillation ( AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [ 11][ 12] It often begins as short periods of abnormal beating, which become longer or continuous over time. [ 4] It may also start as other forms of arrhythmia such as atrial ...
Candesartan. Candesartan is an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure. Candesartan has a very low maintenance dose. Like olmesartan, the metabolism of the drug is unusual as it is a cascading prodrug.
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