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Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers ( e.g., multiple myeloma ), graft-versus-host disease, and many skin disorders ( e.g., complications of leprosy such as skin lesions ). [ 6][ 7][ 8] Thalidomide has been used to treat conditions associated with ...
Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as phocomelia, as well as thousands of ...
Phocomelia is a congenital condition that involves malformations of human arms and legs which results in a flipper-like appendage. [ 1][ 2] A prominent cause of phocomelia is the mother's use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined. [ 2]
Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [ 10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [ 10][ 11] For hives it is a less preferred alternative to antihistamines. [ 10] It has a mild to moderate benefit for sleeping problems. [ 12]
The drug reaches peak concentration in about 2 hours and has a half life in healthy adults of about 2–3 hours. [10] [9] Zolpidem's half life is decreased in children and increased in the elderly and people with liver issues. While some studies show men metabolize zolpidem faster than women (possibly due to testosterone), [51] others do not. [9]
Siriano, 38, and Unisom (the sleep aid medication) have joined forces to expand upon the Met Gala’s “Sleeping Beauties: Reawakening Fashion” theme with an experience in New York City that ...
Secobarbital (as the sodium salt, originally marketed by Eli Lilly and Company for the treatment of insomnia, and subsequently by other companies as described below, under the brand name Seconal) is a short-acting barbiturate derivative drug that was patented in 1934 in the United States. [ 3] It possesses anaesthetic, anticonvulsant ...
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