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Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. [ 30][ 8][ 31] It has been explored as a treatment option for bacterial keratitis.
Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
Many cats become paralyzed because of traumatic injuries, such as a hard fall or being hit by a car. Cats can also experience a type of blood clot called “Saddle thrombus,” which blocks blood ...
Esters of other synthetic corticosteroids. Δ 7 -Prednisolone 21-acetate. Alclometasone dipropionate. Amcinonide (triamcinolone acetate cyclopentanonide) Chloroprednisone acetate. Ciclometasone (a corticosteroid 21- [4- [ (acetylamino)methyl]cyclohexyl]carboxylate ester) Clobetasol propionate. Clobetasone butyrate.