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Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...
Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. [ 30][ 8][ 31] It has been explored as a treatment option for bacterial keratitis.
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
Esters of other synthetic corticosteroids. Δ 7 -Prednisolone 21-acetate. Alclometasone dipropionate. Amcinonide (triamcinolone acetate cyclopentanonide) Chloroprednisone acetate. Ciclometasone (a corticosteroid 21- [4- [ (acetylamino)methyl]cyclohexyl]carboxylate ester) Clobetasol propionate. Clobetasone butyrate.
Prednisolone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester .
Methylprednisolone succinate. Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester —specifically the C21 succinate ester of methylprednisolone —which is used by intravenous administration. [3] [4] Methylprednisolone succinate is provided as ...
Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan ), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. [2] [3] It has been reported to reduce wrinkles in elderly women when ...