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  2. Cytokinetics - Wikipedia

    en.wikipedia.org/wiki/Cytokinetics

    In July 2020, Ji Xing Pharmaceuticals signed a financing deal with Cytokinetics, which included the rights to commercialize the drug designed to treat hypertrophic cardiomyopathies, aficamten, in China and certain neighboring regions. Products. Omecamtiv mecarbil is a cardiac muscle activator for the potential treatment of heart failure.

  3. Cytokinetics heart drug succeeds in closely watched study ...

    www.aol.com/news/cytokinetics-heart-disease-drug...

    Shares of the San Francisco-based Cytokinetics surged over 80% to touch a more than a 19-year high of $83.82, on track to add as much as $3.74 bi Cytokinetics heart drug succeeds in closely ...

  4. Novartis in advanced talks to buy Cytokinetics- source - AOL

    www.aol.com/news/novartis-advanced-talks-buy...

    (Reuters) -Swiss drugmaker Novartis is in the lead to acquire Cytokinetics in a deal that could value the drug developer at well over $10 billion, a source familiar with the matter said on Monday.

  5. Omecamtiv mecarbil - Wikipedia

    en.wikipedia.org/wiki/Omecamtiv_mecarbil

    Omecamtiv mecarbil. Omecamtiv mecarbil ( INN [1] ), previously referred to as CK-1827452, is a cardiac-specific myosin activator. It is an experimental drug being studied for a potential role in the treatment of left ventricular systolic heart failure. [2] Systolic heart failure involves a loss of effective actin -myosin cross bridges in the ...

  6. FDA approves Pfizer's first gene therapy for rare ... - AOL

    www.aol.com/news/fda-approves-pfizer-first-gene...

    The Food and Drug Administration on Friday approved Pfizer ’s treatment for a rare genetic bleeding disorder, making it the company’s first-ever gene therapy to win clearance in the U.S. The ...

  7. Leronlimab - Wikipedia

    en.wikipedia.org/wiki/Leronlimab

    Leronlimab (codenamed PRO 140) is a humanized monoclonal antibody targeted against the CCR5 receptor found on T lymphocytes of the human immune system. It is being investigated as a potential therapy in the treatment of COVID-19, [1] [2] triple negative breast cancer, [3] and HIV infection. [4] The United States Food and Drug Administration has ...

  8. Accelerated approval (FDA) - Wikipedia

    en.wikipedia.org/wiki/Accelerated_approval_(FDA)

    The United States Food and Drug Administration (FDA) initiated the FDA Accelerated Approval Program in 1992 to allow faster approval of drugs for serious conditions that fill an unmet medical need. The faster approval relies on use of surrogate endpoints. [1] Drug approval typically requires clinical trials with endpoints that demonstrate a ...

  9. Novartis drops pursuit of Cytokinetics - source - AOL

    www.aol.com/news/novartis-drops-pursuit...

    Novartis may attempt to pursue a deal for Cytokinetics in the future or a different suitor may acquire the company, the person said. On Monday, Reuters reported that Novartis is in the lead to ...