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  2. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:

  3. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    The elimination half-life of diphenhydramine has not been fully elucidated, but appears to range between 2.4 and 9.3 hours in healthy adults. [6] A 1985 review of antihistamine pharmacokinetics found that the elimination half-life of diphenhydramine ranged between 3.4 and 9.3 hours across five studies, with a median elimination half-life of 4.3 ...

  4. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    H. 1. antagonist. H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic ...

  5. Allergy medications may cause brain damage, increase ... - AOL

    www.aol.com/article/2016/04/19/allergy...

    If you've ever popped a Benadryl or two to sleep through a long flight (or even just a regular night), you can pretty much count yourself among the majority of the population. ... Unisom and the ...

  6. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    In 1971, Sominex was a combination of scopolamine aminoxide hydrobromide, methapyrilene hydrochloride, and salicylamide, [19] the last of which is noted as a pain killer, [20] and comprised the largest part of the formula. [21] This formula was still in use in 1975, [22] [23] 1977, [24] and in 1982. [25] A survey of elderly patients between ...

  7. Doxepin - Wikipedia

    en.wikipedia.org/wiki/Doxepin

    Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [ 10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [ 10][ 11] For hives it is a less preferred alternative to antihistamines. [ 10] It has a mild to moderate benefit for sleeping problems. [ 12]

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