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Sleep can be adversely affected by benzodiazepine dependence. Possible adverse effects on sleep include induction or worsening of sleep disordered breathing. Like alcohol, benzodiazepines are commonly used to treat insomnia in the short term (both prescribed and self-medicated), but worsen sleep in the long term.
As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
In this select population who are naive to and overdose solely on a benzodiazepine, it can be considered. [53] Due to its short half life, the duration of action of flumazenil is usually less than 1 hour, and multiple doses may be needed. [48] When flumazenil is indicated the risks can be reduced or avoided by slow dose titration of flumazenil ...
A drug overdose ( overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [ 2][ 3] Typically it is used for cases when a risk to health will potentially result. [ 2] An overdose may result in a toxic state or death. [ 3]
The short answer is yes, you can overdose on electrolytes. Consuming too many electrolytes may cause an electrolyte imbalance in the body and lead to many of the signs and symptoms The Bohemian ...
The FDA is warning of compounded semaglutide where patients are self-administering incorrect doses of the drug. Many people are finding themselves overdosing on alternatives to Ozempic and Wegovy ...
As one of Ryan Murphy's go-to actors for his “American Horror Story" franchise, Emma Roberts has been sawed in half, played a ruthless witch and a final girl facing off against a serial killer.
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically cyclopyrrolones, used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid ...