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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
H. 1. antagonist. H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic ...
Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
August 11, 2024 at 6:15 PM. U.S. health officials on Friday approved a nasal spray to treat severe allergic reactions, the first needle-free alternative to shots like EpiPen. The Food and Drug ...
Diphenhydramine is effective in treatment of allergies. [23] As of 2007, it was the most commonly used antihistamine for acute allergic reactions in the emergency department. [24] By injection it is often used in addition to epinephrine for anaphylaxis, [25] although as of 2007 its use for this purpose had not been properly studied. [26]
The maker of Robitussin settled a consumer lawsuit that claimed its "non-drowsy" cough and flu medicine causes drowsiness, agreeing to pay $4.5 million and remove the "non-drowsy" claim from its ...
Antihistamines that target the histamine H 1 -receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing). In addition, they may be used to treat insomnia, motion sickness, or vertigo caused by problems with the inner ear. H 2 -antihistamines bind to histamine H 2 receptors in the upper gastrointestinal ...
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