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Chemistry. [edit] Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
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Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
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Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping. [ 1 ][ 11 ] They may have difficulty falling asleep, or staying asleep for as long as desired. [ 1 ][ 9 ][ 12 ] Insomnia is typically followed by daytime sleepiness, low energy, irritability, and a depressed mood. [ 1 ]
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