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[4] [5] It can be given by mouth, by injection into a vein, and as an eye drop. [5] Common side effects include diarrhea, dizziness, and headache. [4] Severe side effects may include spontaneous tendon ruptures, nerve damage, and worsening of myasthenia gravis. [4] Safety of use in pregnancy and breastfeeding is unclear. [6]
The most common side effect is conjunctival hyperaemia (increased bloodflow in the outer layer of the eye), which occurs in over 10% of people taking the drug. Side effects in less than 10% of people include other eye problems such as itching, foreign body sensation or dry eye, as headache or hyperpigmentation (darkening) of the skin around the eye.
Common side effects include red eyes, dry eyes, change in color of the eyes, blurry vision, and cataracts. [ 5 ] [ 6 ] [ 4 ] Use during pregnancy or breastfeeding is generally not recommended. [ 1 ] [ 6 ] [ 4 ] It is a prostaglandin analog and works by increasing the outflow of aqueous fluid from the eyes.
Migraine impacts around 10% of people all over the world. It is important for people to have treatment options, and data like this review may help guide treatment recommendations in the future.
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
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