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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Saridon was first launched by Roche in 1933, initially containing pyrithyldione and phenacetin, widely used remedies for fever and pain. It often contained aspirin, phenacetin and caffeine, but was reformulated in 1981, replacing the original ingredient phenacetin with paracetamol, before phenacetin was banned by the US FDA in 1983. It was ...
Magnesium salicylate. Magnesium salicylate is a common analgesic [ 1] and nonsteroidal anti-inflammatory drug (NSAID) [ 2] used to treat mild to moderate musculoskeletal pain [ 3] such as in tendons and muscles. [citation needed] It is also used to treat joint pain like arthritis, [ 2][ 3] general back pain, [ 4] and headaches. [citation needed]
The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as acetaminophen (paracetamol) in Tylenol PM and ibuprofen in Advil PM. Diphenhydramine can cause minor psychological dependence. [29] Diphenhydramine has also been used as an anxiolytic. [30]
Excedrin is an over-the-counter headache pain reliever, typically in the form of tablets or caplets. It contains paracetamol, aspirin and caffeine. It was manufactured by Bristol-Myers Squibb until it was purchased by Novartis in July 2005 along with other products from BMS's over-the-counter business. As of March 2015, GSK holds majority ...
Somnifacient. Etizolam is a benzodiazepine somnifacient for treating insomnia. Somnifacient (from Latin somnus, sleep [1] ), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines .
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