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2. Ciclosporin - Wikipedia

   en.wikipedia.org/wiki/Ciclosporin

   Ciclosporin is indicated to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants. [8] [7] It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis, [25] [7] and as eye drops for treating dry eyes caused by ...

3. Dry eye syndrome - Wikipedia

   en.wikipedia.org/wiki/Dry_eye_syndrome

   Topical ciclosporin (topical ciclosporin A, tCSA) 0.05% ophthalmic emulsion is an immunosuppressant that is commonly used to treat symptoms of dry eye syndrome. [14] [47] The drug decreases surface inflammation with the goal of increasing tear production. [16]

4. Harrow Health - Wikipedia

   en.wikipedia.org/wiki/Harrow_Health

   In 2017, after launching a $49 per month low-cost compounded cyclosporine-A formulation as a potential competitor to Restasis and a glaucoma eye drop program called Simple Drops, [20] the company, alongside Sinceres, became the target of a suit from Allergan for claims connected to supposed false and misleading marketing statements. [21]

5. Lifitegrast - Wikipedia

   en.wikipedia.org/wiki/Lifitegrast

   Novartis noted that the drug amassed approximately $400 million in revenue in 2018. [11] In 2023, Novartis sold the assets to Bausch + Lomb for $1.75 billion and eligible for an additional $750 million in payments linked to future sales for Xiidra as well as two pipeline assets.

6. Inhaled ciclosporin - Wikipedia

   en.wikipedia.org/wiki/Inhaled_ciclosporin

   Formulation of the drug for inhalation purposes has proved challenging because of ciclosporin's poor aqueous solubility. [5] Consequently, aerosol studies have often employed compatible solvents such as propylene glycol [6] or ethanol [7] as the vehicle for administration by nebulizer or have used more complicated aqueous-based formulations involving liposomes [8] [9] or other dispersions. [10]

7. Prescription drug prices in the United States - Wikipedia

   en.wikipedia.org/wiki/Prescription_drug_prices...

   Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.