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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Although diphenhydramine is widely used and generally considered to be safe for occasional usage, multiple cases of abuse and addiction have been documented. [15] Because the drug is cheap and sold over the counter in most countries, adolescents without access to more sought-after illicit drugs, are particularly at risk. [100]
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16] [17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
Pre-exposure prophylaxis is a general term for the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent. The term PrEP now typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. [ 1] PrEP is one of a number of HIV prevention strategies for ...
Pregnancy over the age of 50 has become possible for more women because of advances in assisted reproductive technology, in particular egg donation. Typically, a woman's fecundity ends with menopause, which, by definition, is 12 consecutive months without any menstrual flow at all. During perimenopause, the menstrual cycle and the periods ...
Vas-occlusive contraception is a form of male contraception that blocks sperm transport in the vas deferens, the tubes that carry sperm from the epididymis to the ejaculatory ducts. Vas-occlusive contraception provides a contraceptive effect through physical blockage of the vas deferens, the duct connecting the epididymis to the urethra.
Gestational diabetes is a condition in which a person without diabetes develops high blood sugar levels during pregnancy. [ 2] Gestational diabetes generally results in few symptoms; [ 2] however, it increases the risk of pre-eclampsia, depression, and of needing a Caesarean section. [ 2] Babies born to individuals with poorly treated ...