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Secukinumab, sold under the brand name Cosentyx among others, is a human IgG1κ monoclonal antibody used for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. [ 4 ] [ 5 ] [ 6 ] It binds to the protein interleukin (IL)-17A and is marketed by Novartis .
Novartis is one of the largest pharmaceutical companies in the world, formed in 1996 by the merger of Ciba-Geigy and Sandoz. Ciba-Geigy was a result of the 1970 merger of two Swiss dye manufacturers, CIBA and Geigy, and had a history of producing drugs, agrochemicals and other products.
A landmark Supreme Court case in India on whether Novartis could patent Gleevec, a cancer drug. The court upheld the rejection of the patent application based on a 2005 amendment to the patent law that required significant efficacy difference for new uses of known drugs.
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3] [4] [5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6]
Nilotinib, sold under the brand name Tasigna marketed worldwide by Novartis, is a medication used to treat chronic myelogenous leukemia (CML) which has the Philadelphia chromosome. [5] It may be used both in initial cases of chronic phase CML as well as in accelerated and chronic phase CML that has not responded to imatinib. [5] [6] It is taken ...
The Novartis Foundation has been one of the leading organizations in the private sector for international development for the last 35 years. The humanitarian engagement of the Novartis Foundation goes back to the 1960s, when the Basel-based companies Ciba, Geigy, Sandoz, Durand & Huguenin, Hoffmann-La Roche and Lonza founded the Basel Foundation for Developing Countries.
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