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  2. Mepyramine - Wikipedia

    en.wikipedia.org/wiki/Mepyramine

    Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H 1 receptor as an inverse agonist. [ 1] Mepyramine rapidly permeates the brain, often causing drowsiness. [ 2] It is often sold as a maleate salt, pyrilamine maleate. The medication has negligible anticholinergic activity, with 130,000-fold selectivity for ...

  3. Pheniramine - Wikipedia

    en.wikipedia.org/wiki/Pheniramine

    Pheniramine. Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines ...

  4. Benadryl - Wikipedia

    en.wikipedia.org/wiki/Benadryl

    [2] Benadryl Allergy is widely used as a sleep aid among adults. While it is not marketed as an over-the-counter (OTC) sleeping aid, most versions of Benadryl contain diphenhydramine, a drug with sedative properties. [6] Diphenhydramine (Benadryl) has also been used by parents to help improve their infant's sleep habits.

  5. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as acetaminophen (paracetamol) in Tylenol PM and ibuprofen in Advil PM. Diphenhydramine can cause minor psychological dependence. [29] Diphenhydramine has also been used as an anxiolytic. [30]

  6. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...

  7. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [ 46 ] with a class A safety rating for pregnancy (no evidence of ...

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