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Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...
Excessive daytime sleepiness ( EDS) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep. EDS can be considered as a broad condition encompassing several sleep disorders where increased sleep is a symptom, or as a symptom of another ...
In the study, the therapy AXS-12 reduced cataplexy attacks by 83% versus 56% for a placebo in a study with 90 patients of narcolepsy with cataplexy, meeting the trial goal.
Diphenhydramine. Diphenhydramine ( DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. [ 11] It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. [ 11]
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically cyclopyrrolones, used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid ...
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