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Other severe side effects include liver problems and low blood cell counts. [3] Use during pregnancy may harm the baby. [3] Propylthiouracil is in the antithyroid family of medications. [4] It works by decreasing the amount of thyroid hormone produced by the thyroid gland and blocking the conversion of thyroxine (T4) to triiodothyronine (T3). [3]
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. [ 3] Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. [ 3] Some, however, use the terms interchangeably. [ 5]
Sheehan's syndrome, also known as postpartum pituitary gland necrosis, occurs when the pituitary gland is damaged due to significant blood loss and hypovolemic shock (ischemic necrosis) usually during or after childbirth leading to decreased functioning of the pituitary gland ( hypopituitarism ). [ 1] The pituitary gland is an endocrine organ ...
Thyroxine-binding globulin ( TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. TBG binds thyroid hormones in circulation. It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.
Congenital iodine deficiency syndrome ( CIDS) is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone ( hypothyroidism) often caused by insufficient dietary iodine during pregnancy. It is one cause of underactive thyroid function at birth, called congenital hypothyroidism ...
Frequency. 0.3–0.4% (USA) [ 8] Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [ 3] It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, muscle aches, constipation ...
Postpartum thyroiditis refers to thyroid dysfunction occurring in the first 12 months after pregnancy [ 1] and may involve hyperthyroidism, hypothyroidism or the two sequentially. According to the National Institute of Health, postpartum thyroiditis affects about 8% of pregnancies. [ 2] There are, however, different rates reported globally.