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The prescription drug, which patients self-inject once a week, is the same medication as Type 2 diabetes treatment Mounjaro, but in different doses to treat obesity, ... Zepbound vs. Ozempic.
A 3-year-study of Zepbound and Mounjaro found the GLP-1 drugs can help prevent diabetes. The weekly injections cut the risk of developing diabetes by 94% among adults with high blood sugar.
Zepbound is a sister medication to Mounjaro. Mounjaro is approved by the FDA for the treatment of type 2 diabetes; Zepbound is approved for weight loss, but they are both tirzepatide, Ali says.
Tirzepatide is an antidiabetic medication used for the treatment of type 2 diabetes [ 9][ 12][ 13][ 14] and for weight loss. [ 10][ 15] Tirzepatide is administered via subcutaneous injections (under the skin). [ 9][ 12] It is sold under the brand names Mounjaro for diabetes treatment, [ 9] and Zepbound for weight loss. [ 10]
In fact, the diabetes medication Mounjaro has been on the Food and Drug Administration’s shortage list since late 2022, while Zepbound, a drug approved for weight loss, appeared on the list in ...
Native GLP-1 is a peptide hormone with a half-life of 2 minutes because it is rapidly cleared by the enzyme dipeptidyl peptidase-4. [27] As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or even less often. [ 27 ]
In a phase 3 clinical trial, Zepbound led to an average weight loss of 22.5% body weight, or about 52 pounds, surpassing all currently available weight loss medications on the market. The ...
In a 2023 randomized clinical trial, 783 participants took tirzepatide (the generic name for Mounjaro and Zepbound) for 36 weeks. Those who stayed on the drug until week 52 lost an additional 5% ...
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