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30,000 (2015) [ 4] Rheumatoid arthritis ( RA) is a long-term autoimmune disorder that primarily affects joints. [ 1] It typically results in warm, swollen, and painful joints. [ 1] Pain and stiffness often worsen following rest. [ 1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the ...
Palindromic rheumatism ( PR) is a syndrome characterised by recurrent, self-resolving inflammatory attacks in and around the joints, and consists of arthritis or periarticular soft tissue inflammation. [ 1] The course is often acute onset, with sudden and rapidly developing attacks or flares. There is pain, redness, swelling, and disability of ...
Pathology. Elevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity and catalyzes the hydrolysis of phosphate esters in a basic environment. The major function of alkaline phosphatase is transporting chemicals across cell membranes. [ 1]
Polymyalgia rheumatica ( PMR) is a syndrome experienced as pain or stiffness, usually in the neck, shoulders, upper arms, and hips, but which may occur all over the body. The pain can be sudden or can occur gradually over a period. Most people with PMR wake up in the morning with pain in their muscles; however, cases have occurred in which the ...
Inflammatory arthritis is a group of diseases which includes: rheumatoid arthritis, psoriatic arthropathy, inflammatory bowel disease, adult-onset Still's disease, scleroderma, juvenile idiopathic arthritis, and systemic lupus erythematosus (SLE).
Non-steroidal anti-inflammatory drugs[ 1][ 3] ( NSAID) [ 1] are members of a therapeutic drug class which reduces pain, [ 4] decreases inflammation, decreases fever, [ 1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds ...
Stages of metabolic dysfunction–associated steatotic liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis. Metabolic dysfunction–associated steatotic liver disease ( MASLD ), previously known as non-alcoholic fatty liver disease ( NAFLD ), [ a ] is a type of chronic liver disease.
Jaccoud arthropathy ( JA ), is a chronic non-erosive reversible joint disorder that may occur after repeated bouts of arthritis. [ 1][ 2] It is caused by inflammation of the joint capsule and subsequent fibrotic retraction, causing ulnar deviation of the fingers, through metacarpophalangeal joint (MCP) subluxation, [ 1][ 3] primarily of the ...