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392 million (2015) [11] Type 2 diabetes ( T2D ), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. [3]
Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [10] [11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [12] Classic symptoms include thirst, polyuria ...
In 1922, metformin was developed for the treatment of type 2 diabetes mellitus. Further developments. Other notable discoveries since the early development of insulin and metformin include: Development of the long acting insulin NPH in the 1940s by Novo Nordisk; Identification of the first of the sulfonylureas in 1942
Diabetes management. The term diabetes includes several different metabolic disorders that all, if left untreated, result in abnormally high concentrations of a sugar called glucose in the blood. Diabetes mellitus type 1 results when the pancreas no longer produces significant amounts of the hormone insulin, usually owing to the autoimmune ...
Type 2 diabetes mellitus is the most common type of diabetes. Treatments include agents that (1) increase the amount of insulin secreted by the pancreas, (2) increase the sensitivity of target organs to insulin, (3) decrease the rate at which glucose is absorbed from the gastrointestinal tract, and (4) increase the loss of glucose through ...
Relatively common [2] Hyperosmolar hyperglycemic state ( HHS ), also known as hyperosmolar non-ketotic state ( HONK ), is a complication of diabetes mellitus in which high blood sugar results in high osmolarity without significant ketoacidosis. [4] [5] Symptoms include signs of dehydration, weakness, leg cramps, vision problems, and an altered ...
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