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Serum creatinine (a blood measurement) is an important indicator of kidney health, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced [ 5] via a biological system involving creatine, phosphocreatine (also known as creatine phosphate), and adenosine ...
In medicine, the urea-to-creatinine ratio ( UCR[ 1] ), known in the United States as BUN-to-creatinine ratio, is the ratio of the blood levels of urea ( BUN) (mmol/L) and creatinine (Cr) (μmol/L). BUN only reflects the nitrogen content of urea (MW 28) and urea measurement reflects the whole of the molecule (MW 60), urea is just over twice BUN ...
The normal range of GFR, adjusted for body surface area, is 100–130 average 125 (mL/min)/(1.73 m 2) in men and 90–120 (mL/min)/(1.73 m 2) in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 (mL/min)/(1.73 m 2 ) until 2 years of age in both sexes, and then it progressively decreases.
Creatinine is the breakdown of creatine in your muscle tissue and occurs after your body digests protein. The breakdown of creatine to creatinine happens more often in people with more muscle mass ...
A major measure of kidney function is the glomerular filtration rate ( GFR ). The glomerular filtration rate is the flow rate of filtered fluid through the kidney. The creatinine clearance rate ( CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
Urine protein/creatinine ratio is a widely used initial method to estimate daily protein excretion in urine. [1] [2] [3] Since the diagnosis and management of proteinuric renal diseases and the staging of chronic kidney disease depend on accurate identification and quantitation of proteinuria, [4] [1] the implementation of the 24-hour urine collection is the most accurate procedure in practice ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
PDB 3b6r. [ 1] Creatine kinase ( CK ), also known as creatine phosphokinase ( CPK) or phosphocreatine kinase, is an enzyme ( EC 2.7.3.2) expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP).
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