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Tirzepatide is an antidiabetic medication used for the treatment of type 2 diabetes [ 9][ 12][ 13][ 14] and for weight loss. [ 10][ 15] Tirzepatide is administered via subcutaneous injections (under the skin). [ 9][ 12] It is sold under the brand names Mounjaro for diabetes treatment, [ 9] and Zepbound for weight loss. [ 10]
Those who took tirzepatide lost a greater percentage of body weight each month, compared to semaglutide: an average of 5.9% of their body weight after 3 months; 10.1% after 6 months; and 15.3% ...
Mounjaro and Zepbound both contain the same active ingredient, tirzepatide. However, this does not necessarily mean they are interchangeable. Mounjaro is specifically FDA-approved for people with ...
In Zepbound and Mounjaro, GIP is paired with GLP-1 receptor agonists, and research shows the duo provides "powerful benefits" for blood sugar control and weight reduction. Off-label
Wegovy and Zepbound have similar side effects. The most common include nausea, diarrhea, vomiting, stomach pain and constipation, according to the drugs’ manufacturers. Some patients find the ...
In the United States, cost is the highest barrier to GLP-1 agonist usage and was reported as the reason for discontinuation in 48.6 percent of US patients who stopped using the drugs. [33] According to another study, GLP-1 agonists are not cost effective for pediatric obesity in the United States.
In a 2023 randomized clinical trial, 783 participants took tirzepatide (the generic name for Mounjaro and Zepbound) for 36 weeks. Those who stayed on the drug until week 52 lost an additional 5% ...
Zepbound vs. Ozempic. Zepbound is specifically approved for weight management in adults with obesity. Ozempic is a Type 2 diabetes treatment to control blood sugar, though it also leads to weight ...