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Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7][4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [10][11] For hives it is a less preferred alternative to antihistamines. [10] It has a mild to moderate benefit for sleeping problems. [12]
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Diphenhydramine, while traditionally known as an antagonist, acts primarily as an inverse agonist of the histamine H 1 receptor. [86] It is a member of the ethanolamine class of antihistaminergic agents. [45] By reversing the effects of histamine on the capillaries, it can reduce the intensity of allergic symptoms.
Siriano, 38, and Unisom (the sleep aid medication) have joined forces to expand upon the Met Gala’s “Sleeping Beauties: Reawakening Fashion” theme with an experience in New York City that ...
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. [11] [16] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and after behavioral changes, such as sleep hygiene, have been tried.
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