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Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation ), and as a mydriatic (to dilate the pupil ).
Homatropine methylbromide ( INN; also known as methylhomatropine bromide) is a quaternary ammonium salt of methylhomatropine. It is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It does not cross the blood–brain barrier.
[1] [2] It contains hydrocodone, as the bitartrate, an opioid agonist; and homatropine, as the methylbromide, a muscarinic antagonist. [ 1 ] [ 2 ] It is taken by mouth . [ 1 ] [ 2 ]
Hydrocodone plus homatropine (Hycodan) in the form of small tablets for coughing and especially neuropathic moderate pain (the homatropine, an anticholinergic, is useful in both of those cases and is a deterrent to intentional overdose) was more widely used than Dicodid and was labelled as a cough medicine in the United States whilst Vicodin ...
Atropa belladonna, commonly known as belladonna or deadly nightshade, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, [ 1] which also includes tomatoes, potatoes and aubergine (eggplant). It is native to Europe and Western Asia, including Turkey. Its distribution extends from Ireland in the west to western Ukraine and ...
Atropine, a tropane alkaloid, is an enantiomeric mixture of d - hyoscyamine and l -hyoscyamine, with most of its physiological effects due to l -hyoscyamine. Its pharmacological effects are due to binding to muscarinic acetylcholine receptors. It is an antimuscarinic agent.
Parasympathomimetic drug. A parasympathomimetic drug, sometimes called a cholinomimetic drug[ 1] or cholinergic receptor stimulating agent, [ 2] is a substance that stimulates the parasympathetic nervous system (PSNS). [ 3][ 2] These chemicals are also called cholinergic drugs because acetylcholine (ACh) is the neurotransmitter used by the PSNS ...
Cycloplegia. Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation. [1] Because of the paralysis of the ciliary muscle, the curvature of the lens can no longer be adjusted to focus on nearby objects. This results in similar problems as those caused by presbyopia, in which the lens has lost elasticity ...